1. Bring MacCready to the Mass Pike Interchange
2. Kill Winlock
3. Kill Barnes
4. Speak to MacCready
5. Continue traveling with MacCready
6. Bring MacCready to Med-Tek Research
7. Enter Med-Tek Research
8. Locate the executive terminal
9. Override containment lockdown
10. Enter Med-Tek sub-level
11. Retrieve cure for MacCready
12. Speak to MacCready
13. Bring cure to Daisy in Goodneighbor
Locations to Explore
- Financial District (Neighborhood)
- Goodneighbor
- The Third Rail
- Mass Pike Interchange
- Med-Tek Research
- Daisy’s Discount
MacCready at the Ready
After visiting Goodneighbor, you hired MacCready despite a verbal altercation with Winlock and Barnes in the VIP room of the Third Rail.
After some exploration (and numerous talks that you initiate), MacCready asks you to bring him to the Mass Pike Interchange to hunt down and kill the two Gunners that were threatening him in Goodneighbor.
MacCready finally feels ready to hunt down the Gunners. Travel to the Mass Pike Interchange (west and slightly north of Greater Boston), and locate the lift slightly north of the world map marker.
Then wade through the Gunners’ camp, massacring anyone named Winlock or Barnes and anyone else in your way.
Afterward, you must continue to make decisions that MacCready deems positive. Continue this until he’s ready to speak again. He tells you about his son.
Preventative Measures
MacCready confided in you that his son is extremely ill and needs a cure that can only be found within a place called Med-Tek Research. The place is close to Malden Township, in the northern part of the Commonwealth.
Enter the facility and fill any Feral Ghouls with lead. The structure is in partial ruins and under a containment alert, but accessing the executive terminal on the upper floor and using a scrap of paper that MacCready gives you shuts down the alarm.
Access the airlock terminal and open it, allowing you to reach an elevator down deeper into the facility. There are still gormless feral corpses to destroy. Locate the Med-Tek Lab
Terminal to open the lab doors. Pick up the vial of “Prevent” from the central lab work surface.
With the antidote for MacCready’s son in hand, travel to Goodneighbor and visit Daisy’s Discounts, where MacCready hands over the serum to Daisy so she can send it on to his son. Your help does not go unnoticed; now continue to explore with MacCready until you gain enough affinity to obtain his perk. See the Companions section of the STAT Chapter for more information.

