You’ve stumbled upon Moxxi’s second Circle of Slaughter. This Natural Selection Annex, run by Captain Cabrera, specializes in creatures. Can you survive the waves of snarling, growling hatred Cabrera will throw at you?
Availability: Talk to Captain Cabrera at the front desk of the Natural Selection Annex. (Natural Selection Annex DLC required.)
Don’t expose yourself more than necessary; many of your foes can use projectile attacks.
The first wave of Round 1 consists entirely of skags, including moderately dangerous Spitter Skags and Adult Skags. After hitting the button in the center of the arena to begin the battle, run to the southeast room and hide behind the cage. Peek out only as much as necessary to snipe the oblivious targets. Occasionally, they’ll catch on and come find you, but you can usually snuff out most of them this way.
The second wave consists of spiderants, and you can beat them with the same strategy. Ideally, wait until they expose their unarmored bodies so you can score the five Critical Hits necessary for the bonus objective.
The third wave consists of a mix of skags and spiderants, which now spawn from the southeast room. If you’re still using that area as cover, be ready to unload with your shotgun. (If you’d prefer to keep sniping, set up camp in one of the northern rooms instead.)
The final wave consists of spiderants and web-shooting Spiderlings, which mostly spawn from the northern rooms.