Footlight Theatre

Slowly step out onto the scaffolding that is high above the floor of the theatre and listen to Atlas as he explains just what that little girl below you really is. Tiptoe across to the other side of the scaffolding and descend the stairs. Watch as a Thuggish Splicer attacks the Little Sister and is promptly annihilated by her protector, the Big Daddy. Little Sisters and Big Daddies have a symbiotic relationship of sorts. She gathers the Adam they need and he keeps her safe. You can’t get to the Little Sister without going through the Big Daddy—and few individuals get through a Big Daddy!

Use the Wrench to break the lock from the gate and continue around the corner past the Vita-Chamber. The Leadhead Splicer that attacks is quite durable and won’t be felled with a simple swing of the Wrench. Consider using the Pistol against her; either that, or hit her with a blast of Electro Bolt to close the distance and move in for the death blow.

Use Electro Bolt to fry the two Thuggish Splicers near the small waterfall at the base of the stairs. Gather up the items from the three storage crates on the floor of the Transit Hub and approach the tunnel leading to Neptune’s Bounty.

Just as you near your destination, the gate suddenly slams in your face and an alarm rings out. Move to the pool of water and use Electro Bolt to fry the pairs of Splicers that leap down from above. An additional Thuggish Splicer moves in from the right, zap him with your plasmid power and knock him out with the Wrench. Eliminate all five Splicers that appear (while being careful to avoid the flame-throwing Security Turret behind the gate), then search the corpses and Lockboxes in the pool of water for items.

Objective 3: Head to Medical Your way to Port Neptune has been blocked by Andrew Ryan. Atlas has told you there is another way to reach Port Neptune through the Medical Pavilion. Get there now!

Atlas is able to open the way leading to the Medical Pavilion, so all is not lost. Head down the corridor opposite the locked gate and jump over the debris. You’ll soon reach a small room filled with television monitors and a large airlock. It’s another trap, only this time the mysterious Andrew Ryan you’ve been hearing about appears on-screen to chat with you—and he’s clearly not happy you’ve come. Atlas gets the airlock open in time for you to make your way to the Medical Pavilion before the army of Thuggish Splicers break through the glass walls and attack.