Objective 4: Sound Like a Big DaddyInside Optimized Eugenics you can find the means to make yourself sound like a Big Daddy. 
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Approach the entrance to Optimized Eugenics and enter the right-hand decontamination room. Hack the Security Camera on the other side of the door and enter the first room on the right. Head to the back of the Live Subject Testing room and go through the door in the far corner. This is where you’ll find the Alarm Expert 2 tonic and, more importantly, the Voicebox Modification Machine. Approach the machine to have your voicebox permanently replaced with that of a Big Daddy.
Little Sister Encounter
Big Daddy: Elite Rosie
There is a Little Sister that comes and goes via the hole next to the Voicebox Modification Machine. While you are in the Live Subject Testing room you may hear the sounds of the Little Sister in the hall outside, or you may instead hear the Big Daddy coming to get her. Either way, wait in the Live Subject Testing room for the Little Sister to make an appearance.
Once you have visual contact with the Little Sister and are certain that it isn’t a lone Elite Rosie coming to get her, launch the attack. The room is small but the cabinets and equipment in the center provide ample cover and opportunity to strafe out of harm’s way. Use Heat-Seeking RPGs and Frag Grenades to destroy the Elite Rosie.
Objective 5: Look Like a Big DaddyInside Failsafe Armored Escorts you can find the means to make yourself look like a Big Daddy. 
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You may have come to Optimized Eugenics for the voicebox, but there are numerous other reasons to have a look around this area. For starters, there is another Power to the People machine in the northwest corner of the area, in the Eugenic Analysis room—just beware of the two RPG Turrets! Additionally, you’ll find two Audio Diaries in this area of Point Prometheus, so keep your eyes peeled if you hope to earn that “Historian” Achievement.
Safe
Contents: 100 Dollars, 6 Incendiary Bolts
There is a safe sitting in the electrified water of the Backup Generator room. Although you can withstand the current with Electric Flesh 2 spliced into your system, those without that tonic need not feel left out. Use Electro Bolt 3 to enter the Security Monitoring room in the center of the Optimized Eugenics wing. There you find an emergency generator override switch. Pull the lever and run back around to the Backup Generator room and quickly hack the safe with an Automatic Hack Tool. Just be sure to get out of the water before the generator kicks back on.
