As you return up the steps from the Manager’s Office, you hear the deranged voice of a female Splicer. There’s no doubt that this Leadhead Splicer will try to kill you, but she does do you a big favor: she managed to break the display case containing the Machine Gun! Take her out, then grab the weapon. The Machine Gun isn’t as accurate as the Rivet Gun, but it packs a very high rate of fire and can mow down enemies faster than any other weapon.
Open the door to the Museum Entrance with Electro Bolt and the Machine Gun in hand. Quickly zap the Thuggish Splicer to the left and open fire on the one straight ahead. There are three more Splicers in the area. Circle around in a clockwise direction, using the Electro Bolt and either the Rivet Gun or Drill to finish them off. Insert the ticket in the verification unit near the door and head inside.
Find a Little Sister In the El DoradoThe train bulkhead door is frozen shut, preventing further progress toward your Little Sister. Sinclair has informed you that you need a Little Sister to get ADAM. This ADAM can give you the ability to thaw the ice blocking your way. Sinclair mentioned that he saw a Little Sister inside the El Dorado Lounge. Go there to see what you can find. 
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