The Parasite eats away at the city, desiring reward without investment, and tearing down works it could never create. Voices of dissent and subversion erode the will of the individual. Progress towards groundbreaking genetic therapies is impeded by a lack of willing test subjects. Persephone Penal Colony, in opposition to the Parasite, offers solution.
Enemies encountered
Thuggish Splicers
Leadhead Splicers
Brute Splicers
Houdini Splicers
Alpha Series
• 835 Maximum ADAM
~5:00 Gather Duration
Trial 1
Weapons
Grenade Launcher
Frag Grenades, Proximity Mines, Heat-Seeking RPGs
Hack Tool
Remote Hack Dart
Plasmids
Incinerate! 2
Telekinesis 2
Tonics
Armored Shell 2
Use the Remote Hack Dart at the start of the Trial to hack the Security Turret above the El Ammo Bandito machine. Hack the Health Station nearest the Little Sister and destroy the Health Station up the stairs to claim a free First-Aid Kit—this Health Station is too far to get any use from injured Splicers. While you are near the upper Health
Station, use Telekinesis to carry the gas cylinder down the stairs for use later.
Set the Little Sister down and use Telekinesis to ready a fuel barrel. Step back from the Little Sister and wait for Splicers to attack before throwing it. Continue to use your Plasmids to beat back the early wave of attackers so you can save your Grenade Launcher ammo for later. Telekinesis 2 can also pick up the corpses of dead Splicers. Use it to fling dead Splicers at other enemies. Wheelchairs also make great projectiles!
Use Telekinesis to catch and throw the Houdini Splicers’ fireballs back at them as you move around the room trying to lure other potent enemies away from the Little Sister. Set a perimeter of Proximity Mines around her and use your Frag Grenades to take out multiple lesser Splicers. Conserve your Heat-Seeking RPGs and Incinerate! 2 fireballs for the Brute Splicers and Alpha Series enemies that attack later in the battle.
Use Telekinesis to hurl wheelchairs at your assailants as a way of conserving ammo.
Trial 2
Weapons
Drill
Shotgun
00 Buck, Solid Slug
Plasmids
Winter Blast 2
Cyclone Trap 2
Tonics
Armored Shell
Freezing Drill
Ice Storm
Those who enjoy using the freeze-and-shatter combo attack are going to really like this Trial. Here you’ll be using the Drill and Shotgun (with expanded clip size upgrade) to beat back the attacking Splicers with Winter Blast 2. Begin your preparations by laying Cyclone Traps near the Gather Corpse and by hacking the vending machines and Health Station nearest the Gather Corpse. Smash the other Health Station for a free First-Aid Kit, then initiate the Gather.
Resist the urge to bore into enemies with your Drill, since that consumes a lot of Drill Fuel, which is expensive. Instead, freeze them with Winter Blast and then either blast them with the Shotgun’s 00 Buck or use Drill Dash or Drill Swing attack to shatter them before they thaw. Save your Solid Slug ammo for the Brute Splicers and Alpha Series enemies that attack later.
Freeze the Alpha Series, switch to the Solid Slug ammo, and aim for the head for maximum damage!
Keep at least four Cyclone Traps in a perimeter around the Little Sister as the battle rages on. You can conserve EVE by using the Freezing Drill tonic to freeze enemies with a melee attack. Swap to the Shotgun to shatter them if you have an abundance of 00 Buck. Just be sure to get good and close to a frozen enemy when using the Shotgun to ensure they shatter with a single pull of the trigger.
Trial 3
Weapons
Rivet Gun
Rivet, Heavy Rivet
Speargun
Spear Ammo
Plasmids
Electro Bolt 2
Decoy 2
Tonics
Armored Shell
Head Hunter
EVE Link
EVE Expert
This Trial has a heavy sniping element to it, but with the benefit of being able to cast Electro Bolt to freeze your enemies in place. Make your preparations by hacking the vending machines and nearest Health Station. Destroy the upper Health Station for a free First-Aid Kit, then initiate the Gather. Set the Decoy up a few steps away from the Little Sister, so you can draw the Splicers in that direction.
It’s best to save the Speargun for later in the battle when its ability to knock enemies away from the Little Sister comes in handy. For the time being, use Electro Bolt to stun enemies long enough for you to line up a headshot with the Rivet Gun. Save the Heavy Rivets for the Brute Splicers and Alpha Series enemies that attack later. Lay a fresh Decoy down as soon as one disappears, especially if you have to dash to a vending machine.
Collect any Spears and purchase more before the Brute Splicers arrive. Remember to stun them in place with Electro Bolt and aim for the head. The Head Hunter tonic, combined with the increased damage (Rivet Gun) and acceleration (Speargun) upgrades help you make quick work of even the tougher enemies. Just make sure your aim is true.
Place a Decoy near the oil spill, then target the fuel barrel with your Rivet Gun when multiple Splicers draw close.
Bonus Trial
Weapons
All
Plasmids
All
Tonics
All
The final Trial is another chance to experiment with all manner of Plasmids and weaponry in your quest to earn all of the Stars. Continue to summon Elite Security Bots, set up a perimeter of Mini-Turrets, and use Hypnotize 3 to befriend the biggest, baddest enemies you can. Consider placing Trap Rivets on the sides of the fuel barrels (gas cylinders will explode when shot with a Trap Rivet) and Proximity Mines near the Little Sister as she goes to work. But most importantly of all, don’t forget to visit the Gene Bank and splice in Deadly Machines, Hardy Machines, and all of the other combat-oriented tonics at your disposal. Enjoy!
Hang out under the walkway near the cells to avoid being shot by the Splicers that spawn on the second floor.