- Each Trial features one Little Sister and one Gather Corpse. The Gather lasts approximately 3:30 in duration.
- Set the Little Sister down at the corpse to begin the Trial, then keep Splicers from interrupting her.
- The ADAM multiplier will climb to a maximum of 4x as she gathers without interruption. The more ADAM you collect, the better your score and grade.
- Only Thuggish, Leadhead, and Spider Splicers will try to interrupt the Little Sister. Big Daddies, Brute Splicers, and Houdini Splicers will only attack the player.
- You only have access to a limited assortment of Plasmids, tonics, weapons, and ammunition types during each Trial.
- You collect money automatically with each enemy killed. Spend this money at vending machines to collect more First-Aid Kits, EVE Hypos, and ammunition. The action will pause while you use the vending machine.
- Pick up the Little Sister as soon as she stops gathering ADAM to end the Trial.
- Complete the Trial to earn Stars. Each successive Trial within a location is worth one, two, or three Stars. Earn Stars to unlock concept art, video trailers, and additional Trials. See the Progress Menu for details.
- There are six areas, each with three Trials and a Bonus Trial. Bonus Trials unlock after you complete all 18 other Trials.
- You will receive an additional 40 ADAM upon completion of the Gather, just as in the main campaign.
