Remember how you waited out the storm and lit the Burger Tank sign during Hard Rain? A similar set of plans is advisable for this Survival Map; consult Stage 5 of the Hard Rain Campaign for further details. Start the match by signalling the boat using the roof switch, but only after inspecting the entire first street area.
The Burger Tank eatery may have too many entrances to effectively guard if you’re wandering around inside the dining area (1), so take up a defensive position behind the counter, so that you can funnel foes and withstand attacks from Special Infected that can’t get through to hurt you.
You have the ladder, side, or rear entrance escape options from this point, too. The roof is great for attacks, but you can easily be knocked off by Special Infected or swarmed if your team isn’t with you.
Defending to the rear of the property (2) is also an option as long as you sidestep foes attempting to slam you into the river. Lay down Molotov or Fuel Can blazes to help hinder your foes.