There is a hole in your mind, or in your Animus memories at least. The timeline jumps 20 years, and you’re suddenly in a very different location. Try to figure out what’s going on there.
Locate the Criminals
Follow the rooftops toward the waypoint in town, but drop to ground level when you get close to your goal. The people you’re looking for are in an alley on the edge of the target circle (not in the center like you might expect).
Close in on the alley and watch as the criminals come after you. Fight off their bravest members, and then go after the clever one that tries to escape. He has Smoke Bombs and pistols, and he’ll use both against you. Try to dodge around the Smoke Bombs, but it’s okay if you run into them. The runner gets a bit ahead, but your quarry eventually slows down when he hits a central plaza. That’s when it’s time to bring him down.
Get too far away from your target and a 25-second timer begins. Hurry to catch up, or else you desynch and have to start the section again.
Finishing this gets you the “The End of Youth” achievement/trophy.