Two varieties of Half-breeds lurk in the game. You encounter two Lycan Elders during boss fights with special combat rules. You fight less powerful, but still formidable, Lycan Soldiers in three different locations using standard weaponry.
Lycan Soldier
The Lycan’s “weapons” are its claws, teeth, and speed. Their approach is swift, so Blacksight can be very helpful and effective against Lycans, especially when combined with the C-81 Maschinenpistole. Here, we’ll recap the strategies for fighting Lycan Soldiers presented in our walkthrough.
How to Dodge a Lycan
When a Lycan attacks, the beast sprints at you, makes a jumping lunge that inflicts damage, and then tries to hurry away before you can shoot. During each Lycan’s approach you see a red-highlighted “X” appear. When you see this prompt, quickly flick the Left Stick to the left or right away from the Lycan and simultaneously press 
on your PS4 controller. Galahad dives and rolls sideways, evading the Lycan’s lunge attack.
How to Fend Off a Lycan
If a Lycan gets in close, it can force you on the defensive and trigger a tense standoff. Tap rapidly when the prompt appears to keep the Half-breed monster from tearing out your delicate, fleshy throat.
How to Kill a Lycan
To kill a Lycan you must first wound it with gunfire. A wounded Lycan drops to the ground, immobilized for a few seconds. Rush to the fallen creature for an “Execution” move—that is, press 
to finish it off with a merciless knife thrust to its heart. Make this move quickly! Lycans recover from gunshot wounds within a few seconds and then rush away.
Here are three basic strategies you can try:
Cut off Lycan approach angles.
Don’t aim too quickly, so you can see any Lycan that rushes you. Once it begins its approach hold 
and adjust your aim to wound it with gunfire. Once you’ve killed a wounded Lycan with the execution move, hurry to the next corner and watch for the next Lycan attack.
Use Blacksight effectively.
Once a Lycan starts its charge, immediately enable Blacksight if you have it available. (Again, check the meter underneath your weapon readout.) You should be able to put the beast into a downed state before it gets close enough to slash you.
Use your Falchion’s Alt-Fire.
The M2 Falchion rifle’s secondary fire is a concussive air blast that can briefly stun a Lycan, knocking it backward. Target a charging Lycan and press 
for knockback, then quickly pump it full of primary fire bullets. When the creature falls wounded, finish it off with the execution move.