10. Eastern Regional Penitentiary
- COLLECTIBLES: Bobblehead (4), Caps Stash (19), Magazine (7), Power Armor
- CRAFTING: Armor (3), Chemistry, Cooking (2), Power Armor (3), Tinker (2), Weapons (2)
- DANGER: Can Chimes! Escaping Gas! Flamethrower! Grenade! Long Drop! Mine! Oil! Tesla Arc! Tripwire! Turret!
- ITEMS: Arms and Ammo+; Harvestable: Rhododendron, Soot Flower; Health and Chems++; Recipe/Mod/Plan; Trunk
- INFO: Expected Enemy: Super Mutant; Scavenge Rating: 5; Size: 4; Sleeping; Threat Level: 10–25
- LOCK: Door (0, 0, 1, 2, 2), Safe (1, 2, 2), Terminal (1, 2, 2)
- ITEM EXAMPLES: Abraxo Cleaner, Addictol, Adjustable Wrench, Alarm Clock, Beer Bottle++, Blast Radius Board Game, Blood Pack+, Blue Paint, Bobby Pin Box, Bonesaw, Broken Lamp, Bunsen Burner, Burnt Fashion Magazine, Cafeteria Tray+, Chessboard, Clothing Iron+, Coffee Cup+, Coffee Pot, Coolant, Desk Fan+, Dirty Ashtray, Economy Wonderglue+, Explorer Outfit, Extinguisher, Fusion Core, Handcuffs, Hooded Rags, Instamash, Lab Bottle, Left Arm Bones, Makeshift Battery+, Microscope, Mr. Handy Fuel, Nuka-Cola+, Nuka-Cola Bottle+, Pack of Cigarettes+, Pen, Penitentiary Key+, Plunger, Prison Collar++, Rat Poison, Salt, Scavenger Outfit, Short 10-mm Auto Pistol, Spatula, Spices, Stew Pot, Straight Jacket+, Surgical Scalpel, Surgical Tray, Surveyor Outfit, Tabletop Picture Frame, Teddy Bear, Telephone+, Tin Can, Tin Canister, Toaster, Tube Flange, Wood Block+, Yardstick, Yellow Paint

Holding infamous ne’er-do-wells like Mad Dog Malone, this large and ancient prison is brimming with foes and a variety of nasty traps; watch your step when exploring. The prison’s walls are mostly intact along the front (south) side, but become increasingly derelict as you reach the rear of the premises, allowing easy access from multiple directions into the exterior yard and multitude of outbuildings, as well as access into the structure itself (which you can also enter via the front doors). The yard’s two garages have almost every type of work station you need to access, though the surrounding towers have turrets that may cause havoc on top of the enemy threats.
Inside, the prison is a confusing mess of tangled metal blocking your path, locked doors (find a penitentiary key in any security room), and a maze of prison cells. Study the adjacent map, and check the names of the areas you’re visiting above each door until you memorize the layout. Expect two main levels to explore, and watch your step!