74. Charleston
- CRAFTING: Chemistry, Cooking
- DANGER: Long Drop! Radiation! Turret!
- ITEMS: Arms and Ammo, Harvestable: Bloodleaf, Rhododendron, Soot Flower, Wild Mutfruit; Health and Chems; Recipe/Mod/Plan; Trunk
- INFO: Expected Enemy: Ghoul, Irradiated Animal, Irradiated Insect, Scorched, Super Mutant; Landmark; Note; Event: The Bell Tolls; Scavenge Rating: 5+++; Size: 5+++; Sleeping; Threat Level: 1–10
- LOCK: Door (0, 1), Safe (U, 1, 1)
- ITEM EXAMPLES: Abraxo Cleaner, Abraxo Cleaner Industrial Grade, Baseball Glove, Blue Table Lamp, Cat Bowl, Charleston Herald—Bell Article, Chef Hat, Clown, Coffee Cup+++, Coffee Pot+, Cooking Pan, Cooking Pot, Coolant, Cop Cap, Covered Saucepan, Cram, Cranberry Moonshine, Cutting Board, Empty Floral Bud Vase, Empty Milk Bottle, Eyeglasses, Faded Visor, Fancy Lads Snack Cakes, Frying Pan, Glass Pitcher, Globe, Hairbrush, Hot Plate, Medical Liquid Nitrogen Dispenser, Mountain Honey, Noodle Cup, Nurse Uniform, Oven Mitt, Pack of Cigarettes, Pork n’ Beans, Sauce Pan, Short Laser Pistol, Sweater Vest and Slacks, Swimsuit, Tabletop Picture Frame, Tall Drinking Glass, Telephone, Test Tube Rack, Tin Pitcher, Toy Car, Toy Rocketship, Wakemaster Alarm Clock, Willow Bud Vase, Yellow Table Lamp+

The city of Charleston encompasses this and the next eight Primary Locations, all within a relatively delineated border (basically the ruins on either side of the empty Kanawha River). Therefore, all information regarding Crafting, Dangers, Items, Information, Locked areas, and Item Examples are specified for those individual locations: This entry simply flags areas of interest outside these locations.
Working northwest to south, there’s plenty to see and do outside of the major locations to investigate. Far west, look for the bridge across Route 83, close to the railyard, with I-59 running east to west, just north of the Hornwright Industrial Headquarters. The major tenement towers (where the Responders have set up a maneuverability test and turret camp) are just east of the Hornwright skyscraper. All are in terrible disrepair. There are plank paths across the (relatively) dry riverbed and a small camp beneath the road underpass when it breaks apart to the northeast. Move toward the remains of Summersville Dam, and there’s a tall apartment building that’s fully explorable (watch your step; it’s a long drop!).
To the south is a grassy cliff, set of shops, apartments, and the remains of a road bridge that Super Mutants have recently used in their incessant gore-collecting plan. Closer to the AVR Medical Center is a Slocum’s Joe coffee shop, and a barber’s, book store, and clothing emporium; all have scraps of loot to pillage. Before you leave Charleston, be sure to visit the Fire Department to the south, where the Responders have set up a trading post.