Pawprint Isle is a small, circular island with four tiny isles in a row next to it. Viewed from above, it looks like a paw print. Acquire a few valuable items from this little isle.
Sea Platform
Sail to the single Sea Platform and climb its ladder. Defeat the enemies there to reveal a chest, which contains a small reward.
Beedle’s Shop Ship
Enter Beedle’s Shop Ship, which slowly sails around this island, to purchase items. Here he sells Hyoi Pears for 10 Rupees, All-Purpose Bait for 30 Rupees, and 30 bombs for 60 Rupees.
Piece of Heart #4 (via Secret Cave)
Clear the grass and brush away from the large dome on the main isle and look for a crawl space leading inside. Crawl through it and then drop into a hole and into a Secret Cave.
This Secret Cave is fairly small and harbors several ChuChu enemies. Defeat each one as you explore the short cavern, until you come to the treasure chest on the other side. Open the chest to get Piece of Heart #4.
If you have a few bombs with you, destroy the two large, gray boulders in this cavern. Each blocks a pathway leading to a treasure chest. Inside one chest is a Joy Pendant; in the other is a Purple Rupee.
Piece of Heart #36 (via Treasure Chart #30)
Find and open Treasure Chart #30 (inside the Tower of the Gods dungeon [E4]) to pull a chest from the Great Sea near Pawprint Isle. The chest contains Piece of Heart #36.
Treasure Chart #46 (via Secret Cave)
One of Pawprint Isle’s “toes” has a cactus-like tree. If you have the Hookshot, latch onto the statue from your boat and pull yourself onto the isle. Drop into a hole there to enter a second Secret Cave.
Here you face one of the most trying battles in the game. Several Wizzrobes attack, each capable of summoning other enemies. You must defeat all six Wizzrobes. A chest then appears, containing Treasure Chart #46.