Runes
A gang tries to ambush you in a dark alley, behind the carriage station. Defeat (or avoid) them, and look in a damaged piece of furniture in their yard. A Rune is inside of it.
Buy or steal the Rune from the black market in the first part of the district.
In the Upper Aventa District, you find a Rune. It’s in a dilapidated Bloodfly building. Take the side route around the Wall of Light and look for a second story balcony to Blink/Far Reach into. The Rune is in back, inside a desk.
Jindosh’s laboratory has many different modules. When you find that room, use a console to bring up the anatomy module and loot that for a Rune.
Get into the main part of the district, when you first start seeing Guards. Turn left and look for a building near some civilians. Go inside, kill Bloodlies, and look for an Outsider Shrine on the third floor.
Bonecharms
From the main street in the district, Blink/Far Reach to get up higher on a short wall of a building. Then, take another jump to get up to a balcony above the road. Go into the office (the mayor’s place as it turns out) and break a china cabinet to get a Bonecharm.
A Bonecharm is sitting out on the second floor of the carriage station. It has a Guard and an Elite Guard near it, but is otherwise quite easy to obtain.
In the Upper Aventa District, you find a Bonecharm inside a guard building near the carriage. Look on the second floor, inside the first room.
This is on the Assessment Chamber level. Go back the chamber itself and seek an Elite Guard who patrols that back side of the level. Deal with her, and then search a small machine room behind her route. A small drawer has a Bonecharm for you.
On the Assessment Chamber level, you find a lever that brings the guest waiting area up and down. Pull this lever and rush into an area between the two floors while the machine is working. This recessed spot goes down to the bottom. Press a button to send it back up. Another recess is up there. Search for a dead body and a Bonecharm.
Blink/Far Reach from where the civilians are standing, in the main district, up to some pipes. Blink/Far Reach again to get onto a balcony that overlooks the area. Climb into an apartment and search for a Black Bonecharm.
Find Jindosh’s bedroom. Use a lever inside of it and rush into a corner room while it descends into a lower area. A Black Bonecharm is down there.
When you’re in the Upper Aventa District, look for this Corrupt Bonecharm. It’s in a small Bloodfly building. After you pass the Wall of Light, look for a large awning. Blink into the window above that, and search the room you discover.
Paintings
Blink/Far Reach from where the civilians are standing, in the main district, up to some pipes. Blink/Far Reach again to get onto a balcony that overlooks the area. Climb into an apartment and immediately grab a Painting that’s next to the balcony.
The mayor’s office is above the main street in the district. Blink up twice to get to its balcony and head inside. A painting is on the left wall.
Go to the Upper Aventa District. Pass a Wall of Light and look for a brown awning. Blink/Far Reach up to an open window above that awning. The room inside has Bloodflies, but it also has a Painting and a Corrupt Bonecharm.
Sokolov is being held at the bottom of the Assessment Chamber. Find him and loot a Painting from his room.
Jindosh’s laboratory has a Painting on the top tier of the room. It’s behind a massive desk.
Search for Jindosh’s bathroom, on the second floor. Use the lever to spin it and see both configurations of the room. A Painting is in one of them.
Blueprints
Pyro-Sonic Casing is in the ticket booth of the carriage station. Get the Key from the black market, open up the booth, and search it for the Blueprint.
Alloy Polarization is in the Upper Aventa District. Search the third floor of the guard building for it. Climb the stairs to that floor, turn left, and look in the room at the end of the hallway.
Get Slug Splintering Wedges from the desk in Jindosh’s laboratory. It’s on the top tier, near a Painting.
Search the desk in the guest’s waiting room for a Blueprint. If you’ve moved the waiting room to another level, use the lever to call it back so that you can search the desk.