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Dead Space Remake Tissue Sample Objective
Image via Prima Games.

Where to Find the Tissue Sample in Dead Space Remake

Thank you Isaac! But our Tissue Sample's in another sector!

One of the bigger features introduced with the Dead Space Remake is the new side missions available from time to time. These ask you to go somewhat off the main path to complete small objectives, though gift you rewards as you do so. One such side mission is technically started early on but won’t have much meaning until later in the game. Here’s where to find the tissue sample in Dead Space Remake.

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Where is the Tissue Sample in Dead Space Remake?

Dead Space Remake Tissue Sample
Image via Prima Games

The reason you’re looking this up is probably that you found the DNA scanner at the beginning of the game, near Nicole’s lab. The scanner simply says Tissue Sample Needed with nothing else to guide you along. Chances are you’ve been scouring around the room for a tissue sample you might’ve missed, but we’re here to tell you not to bother. You’ll be wasting your time.

The tissue sample doesn’t show up until reaching the end of Chapter 5: Lethal Devotion. We aren’t going to say how you get it as there’s a rather interesting way you unlock it (and unexpected at the time). Point is, you’ll come across a small frozen room the minute you complete Chapter 5 and head into Chapter 6 (pictured above). Inside will be a necromorph body part with a glowing pink light on it. Lo and behold, it’s named Tissue Sample. Picking it up will start the second side mission in Dead Space Remake, Premeditated Malpractice. If you’ve made it this far in the guide, you know where to go next.

Related: All Dead Space Remake Difficulty Modes – Listed

Side missions for Dead Space Remake are very interesting, and not just because of the resources you’ll get along the way. They flesh out certain aspects of the original’s story that were glossed over, though are completely avoidable should that not be your style. We recommend doing them, but it’s entirely your choice.

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Shawn Robinson
Shawn is a freelance gaming journalist who's been with Prima Games for a year and a half, writing mainly about FPS games and RPGs. He even brings several years of experience at other sites like The Nerd Stash to the table. While he doesn't bring a fancy degree to the table, he brings immense attention to detail with his guides, reviews, and news, leveraging his decade and a half of gaming knowledge. If he isn't writing about games, he's likely getting zero kills in his favorite FPS or yelling at the game when it was 100% his fault that he died.